Iran has launched a round of missiles targeting Israel, causing damage and injuries in Tel Aviv, as uncertainty swirled over possible talks to end the three-week US-Israel war on Iran.

The missiles triggered air raid sirens in Israel on Tuesday, including in Tel Aviv, where gaping holes were torn through a multistorey apartment building. It was not immediately clear whether the damage was caused by a direct hit or debris from an interception.

Israel’s Magen David Adom emergency medical service said: “Six people were lightly injured at four different sites.”

Police in Tel Aviv said they were dealing with “several impact sites of munitions”.

Israel’s National Fire and Rescue Authority said the search was on for people trapped in one building in Tel Aviv, adding that civilians were found in a shelter in another damaged building.

Meanwhile, the Israeli military said on Tuesday that its jets carried out a wave of strikes in central Tehran on Monday, targeting key command centres, including facilities associated with the Islamic Revolutionary Guard Corps’ intelligence arm and the Iranian Intelligence Ministry. It said more than 50 additional targets were hit overnight, including ballistic missile storage and launch sites.