The betting experts at Africa Picks break down where the smart money sits for England vs Wales at Twickenham.
England open their Six Nations campaign the strongest they have been in a long time. Wales arrive still searching for answers.
An 11-match winning run, backed by autumn victories over elite opposition, has England looking closer to a finished product than at any point in this cycle. Wales, by contrast, are winless in their last 11 Six Nations matches and have not beaten a tier-one nation since the 2023 World Cup. This fixture feels less like a traditional rivalry contest and more like a measure of how clinical England are prepared to be.
The bookies are on the same page, pricing England at -26.5 (England to win by 27 points or over) at odds of 1.75.
That’s where the value lies. England by 27 or more looks a more attractive play than the outright, with the gap between these sides likely to widen as the game wears on.
Wales may land a punch or two through broken play, but over 80 minutes, England’s power, cohesion and bench impact should tell decisively.
A win in the 30-plus range is realistic, not ambitious – and recent results and form guides support this.
Full preview and betting analysis on Africa Picks
The boys expect England to make it 12 Test wins in a row at Twickenham on Saturday. pic.twitter.com/jw3mXqYf90
— SA Rugby magazine (@SARugbymag) February 5, 2026
Photo: David Rogers/Getty Images
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